Madhuca is a genus belongs to the family Sapotaceae. Madhuca is a large evergreen tree distributed many Asian countries including Sri Lanka. Madhuca plant is shady, deciduous tree can be found in small to very large in size. Bark colour varies from brownish grey,yellowish grey or dark brown bark. Leaves are showed simple and alternate pattern..Flowers regular and bisexual.Flowering can be observed from February to May Madhuca tree commonly called as “mi” or “wana mi”in Sinhala and “honey tree” or “butternut tree” in English.In this review study it is aimed to identify potential genetic and phytochemistry analysis that could be develope in to research prospective. Literature survey was done using “Google Scholar” and “NCBI” using search term “Madhuca”.Numerous research articles were obtained based on bio active chemical analysis,pharmacological profiles but fewer in its other utilizations and genetic analysis. Results were shown that the root,bark.leaves, flowers,fruits,seeds of the plant Madhuca carries number of medicinal properties use in purposes like wound healing,bone fracture,skin diseases,rheumatism,headache,diabetic,Anti snake poisioning and astringent etc. Additional to its medicinal value plant Madhuca considered as a multipurpose forest tree for its potential applications as source of food and nutrition,pharmaceutical ingredient,bio-fertilizer in agriculture and bio-fuel in energy solution.Madhuca plants are rich in secondary metabolites like alkaloids,glycocides,sapponins,tannins and phenolic compounds.In Sri Lanka there are seven species of Madhuca are found, among them four are endemic.Up to date there are small number of experiments were conducted on phytochemical analysis of Madhuca plant and less information available on the genetic assessment on genus Madhuca in Sri Lanaka.Hence it is required to conduct studies on specificed chemical constituent analysis of each Madhuca species available in Sri Lanka for its nutritional,medicinal,agricultural and industrial utilization .Molecular authentication of these species via molecular barcoding method for fill gaps in phenotypic and genotypic matters, to open new areas to extract DNA data for biological studies and also to support in store the genetic data in database for future research purposes and efficient sustainable germplasm management of this valuble plant in Sri Lanka.